Buy Prednisolone 5, 10, 20 and 40 mg online

Prednisolone is a synthetic analogue of the hormones cortisone and hydrocortisone. It has anti-inflammatory, antiallergic, antiexudative, antishock, anti-toxic effects.



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Prednisolone Description

General information:

Prednisolone is a drug; it is a synthetic adrenal corticosteroid. Prednisolone, the active metabolite of prednisone (generic Deltasone), was measured in his plasma using a high-pressure liquid chromatography technique. Corticosteroid is a class of chemicals. This medication affects the immunity making people vulnerable to various infections.

Generic name: Prednisolone.

Brand name: Prednisolone.

Medical Use:

Prednisolone 5 mg is used to fight with inflammation in many inflammatory and allergic conditions. Prednisolone treats blood cell cancers and lymph gland cancers. Buy Prednisolone to treat such cases. Prednisolone 5 mg is very useful for treating such conditions as:
*asthma
*hypodermal gangrenous
*ulcerative colitis
*temporal arthritis
*cluster headaches
*acute leukemia
*and others

Precautions:

1) If you have allergy to any ingredient of Prednisolone, you should not take it. 2) Consult a doctor if you decided to buy Prednisolone. 3) You should remember about possible side effects 4) You should not take more than prescribed. 5) Try not to miss doses, if it happened take it as soon as possible. 6) Avoid contact with people who have recently received live vaccines.7) If you are pregnant you should buy Prednisolone only if it is necessary.

Form and how to use:

Prednisolone may be more often found in the form of tablets, they are Prednisolone 5 mg, Prednisolone 10 mg, Prednisolone 20 mg and Prednisolone 40 mg.
You should take this Prednisolone 5 mg by mouth and with food it is necessary, because food helps to prevent stomach upset. The dosage and duration of taking this medication depends on medical conditions. Take Prednisolone 1 to 4 times per day.
Taking Prednisolone 5 mg without prescription may lead to nausea, increased sweating, insomnia, dizziness, shortness of breath, vision changes or other eye problems, increased hunger and many others not listed here. Call a doctor if you noticed such or other cases.

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Interations:

  • With the simultaneous use of prednisolone with NSAIDs, the risk of erosive and ulcerative lesions in the gastrointestinal tract and the development of bleeding increases (in combination with NSAIDs in the treatment of arthritis, a decrease in the GCS dose is possible due to the summation of therapeutic effects).
  • Oral contraceptives increase the level of prednisone in the blood, with the possible increase in therapeutic and side effects.
  • Possible pharmaceutical incompatibility of prednisolone in the form of a solution for intravenous administration with other intravenous injected drugs – it is recommended to inject it separately from other drugs (intravenously bolus (jet) or through another dropper, as a second solution).
  • The simultaneous use of prednisolone with diuretics can lead to increased excretion of potassium from the body and an increased risk of developing heart failure.
  • The simultaneous use of prednisolone with thiazide diuretics can lead to an increase in the excretion of potassium from the body and an increase in the risk of developing heart failure.
  • The simultaneous use of prednisolone with carbonic anhydrase inhibitors can lead to increased excretion of potassium from the body and an increase in the risk of developing heart failure.
  • With the simultaneous use of prednisolone with carbonic anhydrase inhibitors, the risk of osteoporosis may increase.
  • The simultaneous use of prednisolone with tricyclic antidepressants can increase the severity of depression caused by the use of GCS (tricyclic antidepressants are not indicated for the treatment of this side effect).
  • The simultaneous use of prednisolone with tricyclic antidepressants with m-anticholinergic activity increases IOP.
  • Hypokalemia caused by prednisone may increase the degree and duration of muscle blockade by muscle relaxants.
  • The simultaneous use of prednisolone with antihypertensive drugs can cause a decrease in the antihypertensive effect due to sodium and water retention.
  • The simultaneous use of prednisolone with fluoroquinolones increases the risk of tendinitis, in rare cases it can lead to tendon rupture.
  • The simultaneous use of prednisolone with inducers of liver microsomal enzymes leads to a decrease in its concentration in the blood.
  • The simultaneous use of prednisolone with sodium-containing drugs can lead to the development of edema and an increase in blood pressure.
  • With the simultaneous use of prednisolone with cardiac glycosides, their tolerance worsens and the likelihood of developing arrhythmias increases, incl. ventricular premature beats (due to hypokalemia caused by prednisolone).
  • The simultaneous use of prednisolone with indirect anticoagulants weakens (less often – enhances) their effect. Coagulation indicators should be monitored to maintain the desired anticoagulant effect – it may be necessary to adjust the doses of simultaneously used DV.
  • With the simultaneous use of prednisolone with thrombolytics, the risk of bleeding ulcers in the gastrointestinal tract increases.
  • With the simultaneous use of prednisolone with anticoagulants, the risk of bleeding from ulcers in the gastrointestinal tract increases.
  • With the simultaneous use of prednisolone with insulins, their effectiveness decreases (GCS can increase the concentration of glucose in the blood). Dose adjustment of concomitant insulin may be required.
  • With the simultaneous use of prednisolone with oral hypoglycemic drugs, their effectiveness decreases (GCS can increase the concentration of glucose in the blood). Dose adjustment of concurrent oral hypoglycemic drugs may be required.
  • With the simultaneous use of prednisolone with vitamin D, the effect of the latter on the absorption of calcium ions in the intestine decreases.
  • The simultaneous use of prednisolone with m-anticholinergics increases IOP.
  • The simultaneous use of prednisolone with antihistamine drugs increases IOP.
  • The simultaneous use of prednisolone with nitrates increases IOP.
  • With the simultaneous use of prednisolone with loop diuretics, the risk of osteoporosis may increase.
  • The simultaneous use of androgens with prednisone promotes the development of peripheral edema and hirsutism, the appearance of acne.
  • The simultaneous use of steroid anabolic drugs with prednisone promotes the development of peripheral edema and hirsutism, the appearance of acne.
  • Estrogens reduce the clearance of prednisolone, which may be accompanied by an increase in its action. It may be necessary to adjust the dose of prednisolone when increasing or decreasing the dose of concurrently used estrogens.
  • Oral estrogen-containing contraceptives reduce the clearance of prednisolone, which may be accompanied by an increase in its action.
  • Inhibitors of adrenal cortex function may necessitate an increase in the dose of prednisolone.
  • Antipsychotics increase the risk of developing cataracts when used concomitantly with prednisolone.
  • When used concomitantly with vaccines, prednisolone increases the risk of virus activation and infection.
  • When used simultaneously with live antiviral vaccines, prednisolone increases the risk of viral activation.
  • When used concomitantly with prednisolone, immunosuppressants increase the risk of developing infections and lymphoma or other lymphoproliferative disorders caused by the Epstein-Barr virus.
  • The simultaneous use of antacids reduces the absorption of prednisolone in the form of tablets for oral administration.
  • With simultaneous use with antithyroid drugs, the clearance of prednisolone decreases.
  • With simultaneous use with thyroid hormones, the clearance of prednisolone increases.
  • Prednisolone is metabolized by the CYP3A4 isoenzyme. With the simultaneous use of prednisolone with inhibitors of the isoenzyme CYP3A4, PCF is possible (decreased metabolism of prednisolone).
  • Prednisolone is metabolized by the CYP3A4 isoenzyme. With the simultaneous use of prednisolone with inducers of the CYP3A4 isoenzyme, PCF is possible (increased metabolism of prednisolone).
  • It is possible to develop severe weakness with the simultaneous use of anticholinesterase drugs and corticosteroids in patients with severe pseudoparalytic myasthenia gravis. If possible, anticholinesterase therapy should be discontinued 24 hours before starting treatment with prednisone.
  • With simultaneous use with barbiturates, the metabolism of prednisolone increases. An increase in the dose of prednisolone may be required.
  • The simultaneous use of prednisolone with non-potassium-sparing diuretics can lead to an increase in the potassium-excreting effect of GCS – it is necessary to monitor the possible development of hypokalemia.